2. Cell Cycle/DNA Damage Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease Immunology/Inflammation NF-κB
  3. PPAR STING Reactive Oxygen Species
  4. PPARα agonist 4

PPARα agonist 4 (compound BH400) is a PPARα agonist (EC50= 1.2 μM). PPARα agonist 4 also inhibits STING (IC50: 8.1 μM). PPARα agonist 4 reduces the CoCl2-induced production of ROS and LPS-induced secretion of IL-6. The PPARα agonist 4 restores the decreased expression of PCG1α induced by LPS.

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PPARα agonist 4 Chemical Structure

PPARα agonist 4 Chemical Structure

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PPARα agonist 4 Related Antibodies

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Description

PPARα agonist 4 (compound BH400) is a PPARα agonist (EC50= 1.2 μM). PPARα agonist 4 also inhibits STING (IC50: 8.1 μM). PPARα agonist 4 reduces the CoCl2-induced production of ROS and LPS-induced secretion of IL-6. The PPARα agonist 4 restores the decreased expression of PCG1α induced by LPS[1].

Molecular Weight

337.34

Formula

C20H16FNO3
SMILES

O=C(O)C1=CC(NCC2=CC=C(C3=CC=C(F)C=C3)C=C2)=CC=C1O
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Room temperature in continental US; may vary elsewhere.
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PPARα agonist 4 Related Classifications

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Keywords:

PPARα agonist 4PPARα agonist4PPARα agonist-4PPARSTINGReactive Oxygen SpeciesPeroxisome proliferator-activated receptorsStimulator of Interferon GenesTMEM173MITAERISMPYSHMC3 cellmicroglialInhibitorinhibitorinhibit

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