2. Cell Cycle/DNA Damage Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease
  3. PPAR
  4. PPARγ agonist 14

PPARγ agonist 14 (compound 3) is a PPARy agonist (EC50=2.4 μM) with anti-diabetic activity. PPARγ agonist 14 can improve intracellular glucose uptake, promote insulin release, and lower blood sugar. In addition, PPARγ agonist 14 also improves mitochondrial function, reduces oxidative stress, and inhibits inflammatory factors. PPARγ agonist 14 can be used in the study of neurodegenerative diseases, neuroinflammatory diseases, and other diseases.

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PPARγ agonist 14 Chemical Structure

PPARγ agonist 14 Chemical Structure

CAS No. : 6951-57-1

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Based on 1 publication(s) in Google Scholar

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Description

PPARγ agonist 14 (compound 3) is a PPARy agonist (EC50=2.4 μM) with anti-diabetic activity. PPARγ agonist 14 can improve intracellular glucose uptake, promote insulin release, and lower blood sugar. In addition, PPARγ agonist 14 also improves mitochondrial function, reduces oxidative stress, and inhibits inflammatory factors. PPARγ agonist 14 can be used in the study of neurodegenerative diseases, neuroinflammatory diseases, and other diseases[1].

IC50 & Target[1]

PPARγ

2.4 μM (EC50)

Molecular Weight

316.31

Formula

C17H16O6
CAS No.
Appearance

Solid

SMILES

O=C1C2=C(OC)C(O)=C(OC)C=C2OC(C1)C3=CC=C(C=C3)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
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PPARγ agonist 14 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PPARγ agonist 146951-57-1PPARγ agonist14PPARγ agonist-14PPARPeroxisome proliferator-activated receptorsAgonistshypoglycemicoxidative stressinflammatory factorsneurodegenerative diseasesInhibitorinhibitorinhibit

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