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  4. PROTAC SMARCA2/4-degrader-35

PROTAC SMARCA2/4-degrader-35 (Ex.42) is a SMARCA2/4 degrader with a DC50 <2.5 nM. (Target ligand: HY-W874018; E3 ligand: HY-168226; linker: HY-168227; E3 ligand+linker: HY-168228)

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PROTAC SMARCA2/4-degrader-35 Chemical Structure

PROTAC SMARCA2/4-degrader-35 Chemical Structure

CAS No. : 2933253-85-9

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PROTAC SMARCA2/4-degrader-35 Related Antibodies

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von Hippel-Lindau (VHL) Cereblon MDM2 cIAP1

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Description

PROTAC SMARCA2/4-degrader-35 (Ex.42) is a SMARCA2/4 degrader with a DC50 <2.5 nM. (Target ligand: HY-W874018; E3 ligand: HY-168226; linker: HY-168227; E3 ligand+linker: HY-168228)[1]

Molecular Weight

1020.23

Formula

C56H69N13O6
CAS No.
SMILES

OC1=C(C2=CN(C=C(C3=CN(C[C@@H]4C[C@@H](OC5CCN(CC6CCN(C7=NOC([C@H](C(N8C[C@H](O)CC8C(N[C@@H](C)C9=CC=C(C%10=CC=NN%10C)C=C9)=O)=O)C(C)C)=C7)CC6)CC5)C4)N=C3)C(N)=N%11)C%11=N2)C=CC=C1
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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PROTAC SMARCA2/4-degrader-35 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
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Keywords:

PROTAC SMARCA2/4-degrader-352933253-85-9PROTACsSMARCA2/4 degraderPROTACInhibitorinhibitorinhibit

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