2. Recombinant Proteins
  3. Ubiquitin Related Proteins
  4. Ubiquitin Enzymes
  5. E3 Ligases
  6. ITCH Proteins

ITCH Proteins

Related Products

XLSX 3.78 KB

Subscribe Now to the List of Recombinant Proteins

Cat. No. Product Name / Synonyms Species Source
  • HY-P75894
    ITCH/AIP4 Protein, Human (solution)

    E3 ubiquitin-protein ligase Itchy homolog; AIP4; NAPP1; ITCH

    		Human E. coli
    The ITCH/AIP4 protein, a member of the Nedd4 family of ubiquitin ligases, transfers ubiquitin to protein substrates for lysosomal degradation. It regulates cell differentiation and immune responses and is associated with autoimmune disease. Alternative splicing produces multiple isoforms. ITCH/AIP4 is expressed ubiquitously, with notable levels in the testis, esophagus, and 25 other tissues. ITCH/AIP4 Protein, Human (solution) is the recombinant human-derived ITCH/AIP4 protein, expressed by E. coli , with tag free. and with residual Gly-Pro in N-terminal (not related to functional changes).
  • HY-P75894A
    ITCH/AIP4 Protein, Human

    E3 ubiquitin-protein ligase Itchy homolog; AIP4; NAPP1; ITCH

    		Human E. coli
    ITCH/AIP4 protein is an E3 ubiquitin protein ligase that catalyzes the conjugation of “Lys-29”, “Lys-48” and “Lys-63” linked ubiquitin, affecting inflammatory signaling pathways. It forms a ubiquitin editing complex that promotes RIPK1 degradation and terminates TNF- or LPS-mediated NFKB1 activation. ITCH/AIP4 Protein, Human is the recombinant human-derived ITCH/AIP4 protein, expressed by E. coli , with tag free.
Cat. No. Product Name Effect Purity