2. GPCR/G Protein Neuronal Signaling
  3. mGluR
  4. PXT-012253

PXT-012253 is a positron emission tomography (PET) ligand for mGluR4, as it binds to an allosteric site on mGluR4. PXT-012253 can be utilized in researches related to Parkinson's disease and levodopa-induced dyskinesia.

For research use only. We do not sell to patients.

PXT-012253 Chemical Structure

PXT-012253 Chemical Structure

CAS No. : 1835647-08-9

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PXT-012253 Related Antibodies

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Description

PXT-012253 is a positron emission tomography (PET) ligand for mGluR4, as it binds to an allosteric site on mGluR4. PXT-012253 can be utilized in researches related to Parkinson's disease and levodopa-induced dyskinesia[1].

IC50 & Target

mGluR4

 

Molecular Weight

278.76

Formula

C13H11ClN2OS
CAS No.
SMILES

O=C(C1=NC=CC=C1)NC2=CC=C(C(SC)=C2)Cl
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PXT-012253 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PXT-0122531835647-08-9PXT012253PXT 012253mGluRMetabotropic glutamate receptorsPET ligandmGlu4Parkinson's diseaselevodopa-induced dyskinesiaInhibitorinhibitorinhibit

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