2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Pyrimidine-indole hybrid

Pyrimidine-indole hybrid is a compound that inhibits ciliogenesis and has the activity of antagonizing the Hedgehog signaling pathway by destabilizing microtubules. Pyrimidine-indole hybrid exerts its biological effects by inhibiting ciliogenesis and deconstructing the stable form of α-tubulin. Pyrimidine-indole hybrid has shown its unique mechanism of action in in vitro cell experiments and zebrafish embryo models, interfering with microtubule dynamics.

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Pyrimidine-indole hybrid Chemical Structure

Pyrimidine-indole hybrid Chemical Structure

CAS No. : 441742-93-4

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Pyrimidine-indole hybrid Related Antibodies

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Description

Pyrimidine-indole hybrid is a compound that inhibits ciliogenesis and has the activity of antagonizing the Hedgehog signaling pathway by destabilizing microtubules. Pyrimidine-indole hybrid exerts its biological effects by inhibiting ciliogenesis and deconstructing the stable form of α-tubulin. Pyrimidine-indole hybrid has shown its unique mechanism of action in in vitro cell experiments and zebrafish embryo models, interfering with microtubule dynamics[1].

Molecular Weight

361.46

Formula

C20H19N5S
CAS No.
SMILES

CC(NC1=C2C=CC=C1)=C2/C=N/NC3=C4C5=C(SC4=NC=N3)CCCC5
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Room temperature in continental US; may vary elsewhere.
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Purity & Documentation
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Pyrimidine-indole hybrid Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pyrimidine-indole hybrid441742-93-4Endogenous MetaboliteInhibitorinhibitorinhibit

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