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QW30 (Compound 19) shows potent antitumor activity with an IC50 value of 0.33 μM.

For research use only. We do not sell to patients.

QW30 Chemical Structure

QW30 Chemical Structure

CAS No. : 1714112-25-0

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Description

QW30 (Compound 19) shows potent antitumor activity with an IC50 value of 0.33 μM.

Cellular Effect
Cell Line Type Value Description References
DU-145 IC50
0.28 μM
Compound: 19; QW30
Antiproliferative activity against human DU145 cells after 96 hrs by SRB assay
Antiproliferative activity against human DU145 cells after 96 hrs by SRB assay
[PMID: 27187855]
HCT-116 IC50
0.57 μM
Compound: 19; QW30
Antiproliferative activity against human HCT116 cells after 96 hrs by SRB assay
Antiproliferative activity against human HCT116 cells after 96 hrs by SRB assay
[PMID: 27187855]
HL-60 IC50
0.04 μM
Compound: 19; QW30
Antiproliferative activity against human HL60 cells after 96 hrs by SRB assay
Antiproliferative activity against human HL60 cells after 96 hrs by SRB assay
[PMID: 27187855]
HT-29 IC50
0.59 μM
Compound: 19; QW30
Antiproliferative activity against human HT-29 cells after 96 hrs by SRB assay
Antiproliferative activity against human HT-29 cells after 96 hrs by SRB assay
[PMID: 27187855]
MCF7 IC50
0.28 μM
Compound: 19; QW30
Antiproliferative activity against human MCF7 cells after 96 hrs by SRB assay
Antiproliferative activity against human MCF7 cells after 96 hrs by SRB assay
[PMID: 27187855]
MDA-MB-231 IC50
0.32 μM
Compound: 19; QW30
Antiproliferative activity against human MDA-MB-231 cells after 96 hrs by SRB assay
Antiproliferative activity against human MDA-MB-231 cells after 96 hrs by SRB assay
[PMID: 27187855]
PC-3 IC50
0.54 μM
Compound: 19; QW30
Antiproliferative activity against human PC3 cells after 96 hrs by SRB assay
Antiproliferative activity against human PC3 cells after 96 hrs by SRB assay
[PMID: 27187855]
T47D IC50
0.01 μM
Compound: 19; QW30
Antiproliferative activity against human T47D cells after 96 hrs by SRB assay
Antiproliferative activity against human T47D cells after 96 hrs by SRB assay
[PMID: 27187855]
T47D EC50
2.56 nM
Compound: 19; QW30
Inhibition of colony formation in human T47D cells after 7 days by crystal violet staining based assay
Inhibition of colony formation in human T47D cells after 7 days by crystal violet staining based assay
[PMID: 27187855]
T47D EC50
6.42 μM
Compound: 19; QW30
Antimigratory activity in human T47D cells assessed as inhibition of cell migration after 12 hrs by crystal violet staining based transwell migration assay
Antimigratory activity in human T47D cells assessed as inhibition of cell migration after 12 hrs by crystal violet staining based transwell migration assay
[PMID: 27187855]
Molecular Weight

436.59

Formula

C27H36N2O3

CAS No.
SMILES

CC1(C)[C@@H](O)CC[C@]2(C)C3=C(C=C(C(NC4=CC=C(N(C)C)C=C4)=O)C(OC)=C3)CC[C@@]12[H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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QW30 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
QW30
Cat. No.:
HY-143659
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