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  4. (R)-(4′-Hydroxy)-5,7-dihydroxy-4-chromanone

(R)-(4′-Hydroxy)-5,7-dihydroxy-4-chromanone 

Cat. No.: HY-N8178
Handling Instructions

(R)-(4′-Hydroxy)-5,7-dihydroxy-4-chromanone, a homoisoflavonoid, has antiangiogenic activity against human retinal microvascular endothelial cells.

For research use only. We do not sell to patients.

(R)-(4′-Hydroxy)-5,7-dihydroxy-4-chromanone Chemical Structure

(R)-(4′-Hydroxy)-5,7-dihydroxy-4-chromanone Chemical Structure

CAS No. : 849727-88-4

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Description

(R)-(4′-Hydroxy)-5,7-dihydroxy-4-chromanone, a homoisoflavonoid, has antiangiogenic activity against human retinal microvascular endothelial cells[1].

In Vitro

(R)-(4′-Hydroxy)-5,7-dihydroxy-4-chromanone has an GI50 value of 35.8 μM on proliferation of human retinal microvascular endothelial cells (HRECs)[1].
(R)-(4′-Hydroxy)-5,7-dihydroxy-4-chromanone (10 μM, 30 μM, and 100 μM; 8 hours) significantly decreases HRECs overall tubule formation and in a dose-dependent manner[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

286.28

Formula

C16H14O5

CAS No.
SMILES

O=C1[C@H](CC2=CC=C(O)C=C2)COC3=CC(O)=CC(O)=C13

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
(R)-(4′-Hydroxy)-5,7-dihydroxy-4-chromanone
Cat. No.:
HY-N8178
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