1. Neuronal Signaling
  2. Sigma Receptor
  3. (±)-PPCC hemioxalate

(±)-PPCC hemioxalate is a compound that has the ability to regulate the activity of the sigma-1 receptor. (±)-PPCC hemioxalate can selectively bind sigma-1 protein (s1), and then activate s1 receptor leading to dissociation of s1-BIP complex to regulate ER-mitochondrial calcium signaling, which plays an important role in cell bioenergy and cell survival. (±)-PPCC hemioxalate can be used to study sigma-1 receptors in cocaine addiction, forgetting, pain, depression, Alzheimer's disease, stroke, and cancer.

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(±)-PPCC hemioxalate Chemical Structure

(±)-PPCC hemioxalate Chemical Structure

CAS No. : 932736-91-9

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Description

(±)-PPCC hemioxalate is a compound that has the ability to regulate the activity of the sigma-1 receptor. (±)-PPCC hemioxalate can selectively bind sigma-1 protein (s1), and then activate s1 receptor leading to dissociation of s1-BIP complex to regulate ER-mitochondrial calcium signaling, which plays an important role in cell bioenergy and cell survival. (±)-PPCC hemioxalate can be used to study sigma-1 receptors in cocaine addiction, forgetting, pain, depression, Alzheimer's disease, stroke, and cancer[1].

Molecular Weight

424.23

Formula

C24H29NO3.0.5C2H2O4

CAS No.
SMILES

O=C([C@@]1(C2=CC=C(C)C=C2)[C@@H](CN3CCC(C4=CC=CC=C4)(O)CC3)C1)OC.O=C(O)C(O)=O.[0.5]

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Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
(±)-PPCC hemioxalate
Cat. No.:
HY-108514
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