2. Anti-infection Cell Cycle/DNA Damage
  3. Antibiotic DNA/RNA Synthesis
  4. Rachelmycin

Rachelmycin (CC-1065) is an antitumor antibiotic and a DNA-alkylating agent. Rachelmycin has cytotoxic potency that can be used as a cytotoxin to synthesis ADC. Rachelmycin effectively inhibits DNA synthesis. Rachelmycin can be used for cancer and infection research.

For research use only. We do not sell to patients.

Rachelmycin Chemical Structure

Rachelmycin Chemical Structure

CAS No. : 69866-21-3

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Rachelmycin Related Antibodies

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Description

Rachelmycin (CC-1065) is an antitumor antibiotic and a DNA-alkylating agent. Rachelmycin has cytotoxic potency that can be used as a cytotoxin to synthesis ADC. Rachelmycin effectively inhibits DNA synthesis. Rachelmycin can be used for cancer and infection research[1][2][3].

In Vitro

CC-1065 inhibits DNA synthesis, and effects the progression of the cell cycle by blocking cell cycle in G2+M phases[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Rachelmycin Related Antibodies
In Vivo

Rachelmycin (13.5-250 mg/kg; i.p., once daily for 3-9 times) inhibits tumor growth in a variety of mouse tumor models, such as: P388, ADJ-PC6, B16, CD8F1, Colon 26 and L1210 systems[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

703.70

Formula

C37H33N7O8
CAS No.
SMILES

O=C(N1C2=C(O)C(OC)=C3NC(C(N4C5=C(O)C(OC)=C6NC(C(N7C[C@](C8)([H])[C@]98C%10=C(NC=C%10C)C(C=C79)=O)=O)=CC6=C5CC4)=O)=CC3=C2CC1)N
Structure Classification
Initial Source

Streptomyces zelensis
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Rachelmycin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Rachelmycin69866-21-3CC-1065 NSC 298223CC1065CC 1065NSC298223NSC 298223NSC-298223AntibioticDNA/RNA SynthesisStreptomyceszelensisminorgrooveB-formDNAantitumorInhibitorinhibitorinhibit

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