Rapamycin (Standard)

Cat. No.: HY-10219R Purity: ≥98%: FAQs
Handling Instructions

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Rapamycin (Standard) is the analytical standard of Rapamycin. This product is intended for research and analytical applications. Rapamycin (Sirolimus; AY 22989) is a potent and specific mTOR inhibitor with an IC₅₀ of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant.

For research use only. We do not sell to patients.

Rapamycin (Standard) Chemical Structure

CAS No. : 53123-88-9

Size	Price	Stock	Quantity
5 mg	USD 80	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 120	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 192	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 268	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 348	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Product Information
Purity & Documentation
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Description	Rapamycin (Standard) is the analytical standard of Rapamycin . This product is intended for research and analytical applications. Rapamycin (Sirolimus; AY 22989) is a potent and specific mTOR inhibitor with an IC₅₀ of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant.
Molecular Weight	914.17
Formula	C₅₁H₇₉NO₁₃
CAS No.	53123-88-9
Appearance	Solid
Color	White to off-white
SMILES	O=C([C@@]1(O)[C@@H](CC[C@@H](C[C@@H](/C(C)=C/C=C/C=C/[C@H](C[C@@H](C)C([C@@H]([C@@H](/C(C)=C/[C@H]2C)O)OC)=O)C)OC)O1)C)C(N3CCCC[C@H]3C(O[C@@H](CC2=O)[C@@H](C[C@H]4C[C@H]([C@H](O)CC4)OC)C)=O)=O
Structure Classification	Antibiotics Disease Research Anti-inflammation/Immunoregulatory Antibiotics Macrolide Antibiotics
Initial Source	Microorganisms Endogenous metabolite
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Handling Instructions (2659 KB)

Rapamycin (Standard) Related Classifications

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Rapamycin (Standard)53123-88-9mTORFKBPFungalAutophagyEndogenous MetaboliteAntibioticBacterialMammalian target of RapamycinFK506-binding proteinHEK293FKBP12mTORC1autophagyimmunosuppressantInhibitorinhibitorinhibit

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