2. RBP4 ligand-1

RBP4 ligand-1 is a non-retinoid ligands for (RBP4) retinol-binding protein 4. The hRBP4SPA IC50 and RBP4-TTR FRET IC50 values are 0.23±0.11 and 0.13±0.12 μM in the radioligand binding assay and FRET assay, respectively.

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RBP4 ligand-1 Chemical Structure

RBP4 ligand-1 Chemical Structure

CAS No. : 260553-24-0

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RBP4 ligand-1 Related Antibodies

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Description

RBP4 ligand-1 is a non-retinoid ligands for (RBP4) retinol-binding protein 4. The hRBP4SPA IC50 and RBP4-TTR FRET IC50 values are 0.23±0.11 and 0.13±0.12 μM in the radioligand binding assay and FRET assay, respectively[1].

In Vitro

Retinol-Binding Protein 4 (RBP4) is a physiological carrier of retinol (vitamin A) in blood, delivering retinol from the liver to peripheral tissues.RBP4 ligand-1 has the ability to disrupt the RBP4-TTR protein-protein interaction (hRPB4-TTR). The RBP4-TTR FRET IC50 is 0.13±0.12 μM in FRET assay[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

RBP4 ligand-1 Related Antibodies
Molecular Weight

414.81

Formula

C18H18ClF3N4O2
CAS No.
SMILES

FC(F)(C1=C(N2CCN(C(NC3=C(C=CC(Cl)=C3)OC)=O)CC2)N=CC=C1)F
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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RBP4 ligand-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RBP4 ligand-1260553-24-0non-retinoid ligandRBP4protein–protein interactionInhibitorinhibitorinhibit

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