ACAT1 Protein Protein, Human

The ACAT1 protein is a key enzyme in mitochondrial beta-oxidation and plays a crucial role in breaking down fatty acids into acetyl-CoA. In the final step, ACAT1 catalyzes the thiolytic cleavage of 3-oxoacyl-CoA to generate acetyl-CoA and shortened fatty acyl-CoA. ACAT1 Protein Protein, Human is the recombinant human-derived ACAT1, expressed by E. coli , with tag Free labeled tag. The total length of ACAT1 Protein Protein, Human is 394 a.a.,

The ACAT1 protein is a pivotal enzyme in the mitochondrial beta-oxidation pathway, a vital aerobic process responsible for breaking down fatty acids into acetyl-CoA. Operating in the last step of this pathway, ACAT1 utilizes free coenzyme A (CoA) to catalyze the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs, generating acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. This reversible enzymatic activity extends to the condensation of two acetyl-CoA molecules into acetoacetyl-CoA, underscoring ACAT1's essential role in ketone body metabolism. The multifaceted functions of ACAT1 illuminate its significance in regulating key metabolic processes, shedding light on its integral role in maintaining cellular energy balance and homeostasis.

Human

E. coli

Tag Free

P24752-1 (V34-L427)

38

41.4 kDa

Greater than 90 % as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.