ADH4 Protein, Human (GST)

ADH4 Protein, an enzyme, is involved in the metabolism of alcohol and other toxic compounds. Dysregulation of ADH4 Protein has been linked to alcohol-induced liver damage and susceptibility to certain diseases. Targeting ADH4 Protein may offer potential therapeutic interventions by modulating alcohol metabolism, protecting against liver damage, and reducing disease risk. ADH4 Protein, Human (GST) is the recombinant human-derived ADH4 protein, expressed by E. coli , with N-GST labeled tag. The total length of ADH4 Protein, Human (GST) is 380 a.a., .

The ADH4 protein exhibits catalytic activity dependent on NAD, enabling the oxidation of either all-trans-retinol or 9-cis-retinol. Additionally, it has been observed to oxidize long chain omega-hydroxy fatty acids, including 20-HETE, resulting in the production of both the intermediate aldehyde, 20-oxoarachidonate, and the end product, a dicarboxylic acid known as (5Z,8Z,11Z,14Z)-eicosatetraenedioate. Furthermore, ADH4 protein is involved in the reduction of benzoquinones.

Human

E. coli

N-GST

P08319 (M1-F380)

127

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.