AMHR2/MISRII Protein, Human (HEK293, Fc)

AMHR2/MISRII Protein, upon ligand binding, forms a receptor complex with two type II and two type I kinases. Type II receptors activate type I receptors through phosphorylation, leading to autophosphorylation. Activated type I receptors engage SMAD transcriptional regulators, initiating downstream signaling pathways. Crucially, AMHR2/MISRII acts as a receptor for anti-Muellerian hormone, mediating cellular responses triggered by the hormone. AMHR2/MISRII Protein, Human (HEK293, Fc) is the recombinant human-derived AMHR2/MISRII protein, expressed by HEK293 , with C-hFc labeled tag. The total length of AMHR2/MISRII Protein, Human (HEK293, Fc) is 127 a.a., with molecular weight of 50-65 kDa.

Upon ligand binding, AMHR2/MISRII Protein assembles into a receptor complex composed of two type II and two type I transmembrane serine/threonine kinases. The type II receptors phosphorylate and activate the type I receptors, initiating their autophosphorylation. Subsequently, these activated type I receptors engage with SMAD transcriptional regulators, leading to the activation of downstream signaling pathways. Notably, AMHR2/MISRII serves as a receptor for anti-Muellerian hormone, playing a crucial role in mediating the cellular responses triggered by this hormone.

Human

HEK293

C-hFc

Q16671 (P18-S144)

269  [NCBI]

50-65 kDa

Greater than 95% as determined by Tris-Bis PAGE.

<1 EU/μg, determined by LAL method.