Annexin A8/ANXA8 Protein, Human (His)

The annexin A8 (ANXA8) protein acts as an anticoagulant, indirectly inhibiting the thromboplastin-specific complex in the coagulation cascade. Its regulatory role underscores its importance in regulating key components of the coagulation pathway, highlighting its potential to influence the delicate balance between pro- and anticoagulant factors. Annexin A8/ANXA8 Protein, Human (His) is the recombinant human-derived Annexin A8/ANXA8 protein, expressed by E. coli , with N-6*His labeled tag.

Annexin A8 (ANXA8) protein functions as an anticoagulant, operating as an indirect inhibitor of the thromboplastin-specific complex within the blood coagulation cascade. Its regulatory role in modulating the thromboplastin-specific complex emphasizes its significance in influencing key components of the coagulation pathway, suggesting its potential contribution to the delicate balance between procoagulant and anticoagulant factors in blood clotting processes. ANXA8's ability to intervene in thromboplastin-related interactions underscores its importance as a modulator in the intricate network of regulatory mechanisms that govern blood coagulation, shedding light on its potential therapeutic implications in managing coagulation disorders.

Human

E. coli

N-6*His

P13928-1 (M1-P327)

653145  [NCBI]

MAWWKSWIEQEGVTVKSSSHFNPDPDAETLYKAMKGIGTNEQAIIDVLTKRSNTQRQQIAKSFKAQFGKDLTETLKSELSGKFERLIVALMYPPYRYEAKELHDAMKGLGTKEGVIIEILASRTKNQLREIMKAYEEDYGSSLEEDIQADTSGYLERILVCLLQGSRDDVSSFVDPGLALQDAQDLYAAGEKIRGTDEMKFITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQNLHSYFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSMIMEDTSGDYKNALLSLVGSDP

Approximately 38 kDa

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  Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized powder.

Lyophilized from sterile 50 mM Tris-HCL, 300 mM NaCl, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.