Annexin A4/ANXA4 Protein, Mouse (His-Myc)

The Annexin A4/ANXA4 protein is a calcium/phospholipid-binding protein that plays a key role in membrane dynamics by promoting membrane fusion and exocytosis. This protein exhibits specific affinity for calcium ions and phospholipids, allowing it to participate in cellular processes involving membrane interactions. Annexin A4/ANXA4 Protein, Mouse (His-Myc) is the recombinant mouse-derived Annexin A4/ANXA4 protein, expressed by E. coli , with N-10*His, C-Myc labeled tag. The total length of Annexin A4/ANXA4 Protein, Mouse (His-Myc) is 318 a.a., with molecular weight of ~40.8 kDa.

Annexin A4 (ANXA4) is a calcium/phospholipid-binding protein known for its crucial role in membrane fusion and participation in exocytosis. Functioning as a mediator between calcium signaling and membrane dynamics, ANXA4 contributes to cellular processes involved in the release of cellular contents. Its ability to bind to both calcium ions and phospholipids suggests a regulatory role in membrane-related events, particularly those associated with vesicle trafficking and exocytosis. It has to highlight ANXA4's significance in calcium-dependent cellular mechanisms, emphasizing its involvement in promoting membrane fusion and facilitating exocytotic processes.

Mouse

E. coli

N-10*His;C-Myc

P97429 (E2-D319)

11746  [NCBI]

EAKGGTVKAASGFNATEDAQTLRKAMKGLGTDEDAIIGILAYRNTAQRQEIRSAYKSTIGRDLIEDLKSELSSNFEQVILGLMTPTVLYDVQELRRAMKGAGTDEGCLIEILASRTPEEIRRINQTYQQQYGRSLEEDICSDTSFMFQRVLVSLSAAGRDEGNYLDDALMKQDAQELYEAGEKRWGTDEVKFLSILCSRNRNHLLHVFDEYKRISQKDIEQSIKSETSGSFEDALLAIVKCMRSKPSYFAERLYKSMKGLGTDDNTLIRVMVSRAEIDMLDIRASFKRLYGKSLYSFIKGDTSGDYRKVLLVLCGGDD

Approximately 40.8 kDa

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized powder.

Lyophilized from a 0.2 μm solution of 20 mM Tris-HC1, 0.5 M NaCl, 6% Trehalose, pH 8.0.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US;may vary elsewhere.