BTN1A1 Protein, Human (Biotinylated, HEK293, His-Avi)

BTN1A1 Protein is implicated in milk-fat droplet secretion and may serve as a membrane-associated receptor in lactation processes. Additionally, it exhibits immune-regulatory functions, inhibiting T-cell proliferation and modulating cytokine secretion. BTN1A1's association with xanthine dehydrogenase/oxidase suggests diverse cellular functions, inviting further exploration into its role in various biological pathways. BTN1A1 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived BTN1A1 protein, expressed by HEK293 , with C-Avi, C-6*His labeled tag. The total length of BTN1A1 Protein, Human (Biotinylated, HEK293, His-Avi) is 216 a.a., with molecular weight of 35-40 kDa.

BTN1A1 Protein is suggested to play a role in the secretion of milk-fat droplets, indicating its potential involvement in the complex processes associated with lactation. Additionally, it may act as a specific membrane-associated receptor facilitating the association of cytoplasmic droplets with the apical plasma membrane, as suggested by similarity analyses. Moreover, BTN1A1 exhibits inhibitory effects on the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, impacting T-cell metabolism, and modulating the secretion of IL2 and IFNG, highlighting its potential role in immune regulation. Notably, BTN1A1 also appears to associate with xanthine dehydrogenase/oxidase, raising further questions about its diverse cellular functions and potential implications in various biological pathways.

Human

HEK293

C-Avi;C-6*His

Q13410 (A27-R242)

696  [NCBI]

SAPFDVIGPPEPILAVVGEDAELPCRLSPNASAEHLELRWFRKKVSPAVLVHRDGREQEAEQMPEYRGRATLVQDGIAKGRVALRIRGVRVSDDGEYTCFFREDGSYEEALVHLKVAALGSDPHISMQVQENGEICLECTSVGWYPEPQVQWRTSKGEKFPSTSESRNPDEEGLFTVAASVIIRDTSAKNVSCYIQNLLLGQEKKVEISIPASSLPR

35-40 kDa

Greater than 95% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.