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  3. Cathelicidin-4/CATHL4 Protein, Bovine (His-SUMO)

Cathelicidin-4/CATHL4 Protein, Bovine (His-SUMO)

Cat. No.: HY-P71468
Handling Instructions

Cathelicidin-4/CATHL4 protein has potent bactericidal activity and can effectively target Staphylococcus aureus and Escherichia coli. This antibacterial ability makes cathelicidin-4 an important innate immune effector that contributes to host defense against bacterial pathogens. Cathelicidin-4/CATHL4 Protein, Bovine (His-SUMO) is the recombinant bovine-derived Cathelicidin-4/CATHL4 protein, expressed by E. coli , with N-His, N-SUMO labeled tag.

For research use only. We do not sell to patients.

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  • Biological Activity

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  • Documentation

Description

Cathelicidin-4/CATHL4 protein has potent bactericidal activity and can effectively target Staphylococcus aureus and Escherichia coli. This antibacterial ability makes cathelicidin-4 an important innate immune effector that contributes to host defense against bacterial pathogens. Cathelicidin-4/CATHL4 Protein, Bovine (His-SUMO) is the recombinant bovine-derived Cathelicidin-4/CATHL4 protein, expressed by E. coli , with N-His, N-SUMO labeled tag.

Background

Cathelicidin-4/CATHL4 Protein exhibits potent microbicidal activity, demonstrating effectiveness against both S. aureus and E. coli. This antimicrobial property underscores the significance of Cathelicidin-4 in host defense mechanisms, highlighting its role as an innate immune effector capable of combating bacterial pathogens. The broad-spectrum antimicrobial activity against Gram-positive (S. aureus) and Gram-negative (E. coli) bacteria emphasizes the versatility of Cathelicidin-4, making it a valuable component of the host's arsenal in the ongoing battle against microbial invaders.

Species

Bovine

Source

E. coli

Tag

N-His;N-SUMO

Accession

P33046 (I131-R143)

Gene ID

282166  [NCBI]

Molecular Construction
N-term
6*His-SUMO
CATHL4 (I131-R143)
Accession # P33046
C-term
Synonyms
CATHL4; Cathelicidin-4; Indolicidin
AA Sequence

ILPWKWPWWPWRR

Molecular Weight

Approximately 17.9 kDa

Purity

Greater than 90% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

Cathelicidin-4/CATHL4 Protein, Bovine (His-SUMO) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
Cathelicidin-4/CATHL4 Protein, Bovine (His-SUMO)
Cat. No.:
HY-P71468
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