CD30/TNFRSF8 Protein, Cynomolgus (194a.a, HEK293, His)

CD30/TNFRSF8 protein (TNFSF8/CD30L receptor) is a key factor regulating cell growth and lymphoblast transformation and may activate NF-kappa-B signaling. CD30/TNFRSF8 Protein, Cynomolgus (194a.a, HEK293, His) is the recombinant cynomolgus-derived CD30/TNFRSF8 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD30/TNFRSF8 Protein, Cynomolgus (HEK293, His) is 194 a.a., with molecular weight of 37-41 kDa.

CD30/TNFRSF8 protein, as a receptor for TNFSF8/CD30L, plays a key role in the regulation of cell growth and transformation of activated lymphoblasts. In addition, it may participate in the regulation of gene expression through the activation of NF-kappa-B signaling, thereby promoting a variety of cellular processes.

Measured by its binding ability in a functional ELISA. When Recombinant Human CD30L Protein is immobilized at 2µg/mL (100µL/well) can bind Cynomolgus CD30 Protein. The ED₅₀ for this effect is 55.31 ng/mL.

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  Measured by its binding ability in a functional ELISA. When Recombinant Human CD30L Protein is immobilized at 2 µg/mL (100 µL/well) can bind Cynomolgus CD30 Protein. The ED₅₀ for this effect is 55.31 ng/mL.

Cynomolgus

HEK293

C-6*His

XP_015298065 (M1-G194)

102137811  [NCBI]

MPLRGGTRLAQEAASKLTRAPGSPSSVGRPSSDPGLSPTQPCPQGSGDCRKQCEPDYYLDEAGRCTACVSCSRDDLVEKTPCAWNSSRICECRPGMICATSATNSCARCVPYPICAAETGTKPQDMAEKDTTFEAPPVGTQPDCSPTPENGEAPASTSPTLSSLVDSQASKTLPIPTSAPIALSSTGKPVLDAG

Approximately 32-55 kDa due to the glycosylation.

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized powder

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.