CEACAM5 Protein, Mouse (HEK293, His)

The CEACAM5 protein is a key cell surface glycoprotein that promotes cell adhesion, signaling, and tumor progression. It interacts with CEACAM6 and other related molecules to support homo- and hetero-sex adhesion. CEACAM5 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CEACAM5 protein, expressed by HEK293 , with C-His labeled tag.

The CEACAM5 protein, a cell surface glycoprotein, assumes a pivotal role in cell adhesion, intracellular signaling, and tumor progression. It facilitates both homophilic and heterophilic cell adhesion, engaging with other carcinoembryonic antigen-related cell adhesion molecules, notably CEACAM6. Functioning as an oncogene, CEACAM5 contributes to tumor progression by inducing resistance to anoikis in colorectal carcinoma cells. This glycoprotein forms homodimers, emphasizing its role as a multifaceted regulator in cellular interactions and signaling pathways, particularly influencing processes associated with cancer development and progression.

Mouse

HEK293

C-His

Q3UKK2 (Q35-E947)

73250  [NCBI]

QITIELEPPQVIEGENVLIRVNNLTENLITLAWFRGMRIKSPQIGQYTPATKVTVLGPGHSGRETLYSNGSLQIYNVTQEDIGFYSLRIINKHAEIVSITSIYLNVYSSLWTCEHPSPHAKLTIESVPPGISEGGSVLLLVKNLPQNLLSLFWYKGVIAVKKFEIARHIKATNSSVPGPAHTGRETVFSNGSLLLQEVMQSDTGFYTLRTMSTDLKDEVAHVQLYMDTYLLTCYHPLQVKIESLPQNVAVGKTVLLLVHNLPEDFQAFFWYKSAYRRDTYKIAEYKRAMDATILGSAYSSREFIYNNGSMLIIDVTEDDAGYFLLEILREDLKIEKAYIQLHVNSFVSNSKDSASTARLSIESVPPSIVEGGSVLLLVHNLPKNLQSLFWYKGMIAEKKSELIQHIIATSSSLPGPAHSGRETVYNNGSLLLQRVMQNDTQFYTLQTMDTDLKYEVAHVQLQLDTSLSTWYHPLQVKIESLPRNVAVGKSVLFLVHNFPEVFRAFSWYKPAYKSHTSKIVEYHRFTDSATVGAAYRGIEVIFTNGSMVMIDVTEDDAGFYMLEILREDFKVEKAYVQLHVNSFVPNSKVSVSTARLSIESVPPSIVGGESVLLLVHNLPKNLQSLFWYKGVIAEEKSELIQHIIATSSSLPGPAHSGRETVYSNGSLLLQRVMQNDTGFYTLLTMSTDLKDEIAHVQLQLDTSTCCSLLTSDQLIIVPVPRNIAVGKSVLLLVCNVPKDVQTIFWYKSVYRTDIFKIAEYSRSMESTIWGLAHSGKEMVYTNGSLLIQNVTEHDAGLYMLEILHKDYKLERAHVQVHVNNPVSWPFVRVTDTTVRVQSSVVFTCFSADPGVSIRWLFNKQSLQLTERMTLSPSKCQLSIDPVWREDAGKYQCEVSNPVSSKSSLPVRLAVIEE

100-120 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized powder

Lyophilized a 0.22 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4 or PBS, 6% Trehalose, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.