FGA Protein, Human (His)

FGA Protein, a heterohexamer, features a complex structure with disulfide-linked alpha, beta, and gamma chains forming two distinct sets. The heterotrimeric units adopt a head-to-head conformation, converging at the N-termini in a compact central domain. This unique arrangement highlights the intricate organization of FGA, emphasizing the interplay between its constituent subunits essential for its biological functions. FGA Protein, Human (His) is the recombinant human-derived FGA protein, expressed by E. coli , with N-6*His labeled tag. The total length of FGA Protein, Human (His) is 183 a.a., with molecular weight of ~27 kDa.

FGA Protein exists as a heterohexamer, intricately structured through disulfide linkages, comprising two distinct sets of three non-identical chains: alpha, beta, and gamma. The heterotrimeric units arrange themselves in a head-to-head conformation, with the N-termini converging in a compact central domain. This unique arrangement underscores the complex organization of FGA, showcasing its structural intricacies and the interplay between its constituent subunits, which are crucial for its functional roles within biological systems.

Human

E. coli

N-6*His

Q8WW76 (G36-S218)

/

GPRVVERHQSACKDSDWPFCSGEDWNYKCPSGCRMKGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSHSLTTNIMEILRGDFSSANNRDNTYNRVSEDLRSRIEVLKRKVIEKVTANNLLVARVTTEETPHLKARAIKWQMRPEVKPIMKEHIAPREAMLNLALSEVSTLLLWGSLPCPPRLS

Approximately 27 kDa

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized powder

Lyophilized from a 0.2 μm solution of 10 mM Tris-HCl, 1 mM EDTA, 6% Trehalose, pH 8.0.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.