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  4. FGFR1OP Protein, Human (sf9, His-GST)

FGFR1OP Protein, Human (sf9, His-GST)

Cat. No.: HY-P76927
Handling Instructions

FGFR1OP is critical for microtubule dynamics, anchoring microtubules at centrosomes, which is critical for cell organization. It plays an integral role in cilia formation and helps control the complex process of cilia formation. FGFR1OP Protein, Human (sf9, His-GST) is the recombinant human-derived FGFR1OP protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of FGFR1OP Protein, Human (sf9, His-GST) is 378 a.a., with molecular weight of ~69 kDa.

For research use only. We do not sell to patients.

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Description

FGFR1OP is critical for microtubule dynamics, anchoring microtubules at centrosomes, which is critical for cell organization. It plays an integral role in cilia formation and helps control the complex process of cilia formation. FGFR1OP Protein, Human (sf9, His-GST) is the recombinant human-derived FGFR1OP protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of FGFR1OP Protein, Human (sf9, His-GST) is 378 a.a., with molecular weight of ~69 kDa.

Background

FGFR1OP plays a crucial role in microtubule dynamics by serving as an essential factor for anchoring microtubules to the centrosomes, emphasizing its significance in cellular organization. Furthermore, FGFR1OP is indispensable for ciliation, contributing to the intricate processes that govern the formation and maintenance of cellular cilia. Structurally, FGFR1OP forms homodimers and is a component of a ternary complex, along with CEP350 and MAPRE1, highlighting its participation in molecular interactions critical for centrosomal and microtubule-associated functions. The direct interactions of FGFR1OP with CEP350 and MAPRE1 underscore its role in coordinating the assembly and organization of cellular structures. Additionally, FGFR1OP engages with CEP19, further expanding its network of interactions and implicating its involvement in various cellular processes.

Species

Human

Source

Sf9 insect cells

Tag

N-His;N-GST

Accession

O95684-2 (A2-A379)

Gene ID
Molecular Construction
N-term
His-GST
FGFR1OP (A2-A379)
Accession # O95684-2
C-term
Synonyms
Centrosomal protein 43; FGFR1 oncogene partner; CEP43; FOP
Molecular Weight

Approximately 69 kDa

Purity

Greater than 85% as determined by reducing SDS-PAGE

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

FGFR1OP Protein, Human (sf9, His-GST) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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FGFR1OP Protein, Human (sf9, His-GST)
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HY-P76927
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