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Fibromodulin Protein, Human (HEK293, hFc)

Cat. No.: HY-P75186
Handling Instructions

Fibromodulin is an important regulatory protein that affects fiber formation rate and plays a crucial role in collagen fiber formation. It binds type I and type II collagen, affects fibril formation and organization, and contributes to the structural integrity of the extracellular matrix. Fibromodulin Protein, Human (HEK293, hFc) is the recombinant human-derived Fibromodulin protein, expressed by HEK293 , with C-hFc labeled tag.

For research use only. We do not sell to patients.

Surface Plasmon Resonance (SPR) Assay Service   Protein Expression Service

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Top Publications Citing Use of Products
  • Biological Activity

  • Technical Parameters

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  • Documentation

Description

Fibromodulin is an important regulatory protein that affects fiber formation rate and plays a crucial role in collagen fiber formation. It binds type I and type II collagen, affects fibril formation and organization, and contributes to the structural integrity of the extracellular matrix. Fibromodulin Protein, Human (HEK293, hFc) is the recombinant human-derived Fibromodulin protein, expressed by HEK293 , with C-hFc labeled tag.

Background

Fibromodulin Protein, a crucial regulator, influences the rate of fibril formation and is implicated in collagen fibrillogenesis, potentially playing a primary role in this process. Known to bind both type I and type II collagen, Fibromodulin exerts its impact on the formation and organization of fibrils, contributing to the structural integrity of the extracellular matrix. Its interactions with various collagen types underline its significance in modulating fibrillogenesis and maintaining the architecture of connective tissues, highlighting its pivotal role in the extracellular matrix dynamics.

Species

Human

Source

HEK293

Tag

C-hFc

Accession

Q06828/NP_002014.2 (Q19-I376)

Gene ID
Molecular Construction
N-term
Fibromodulin (Q19-I376)
Accession # Q06828/NP_002014.2
hFc
C-term
Synonyms
Fibromodulin; FM; FMOD; KSPG fibromodulin; SLRR2E
Molecular Weight

Approximately 68.2 kDa

Purity

Greater than 90% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

Fibromodulin Protein, Human (HEK293, hFc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
Fibromodulin Protein, Human (HEK293, hFc)
Cat. No.:
HY-P75186
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