GM-CSF R alpha Protein, Cynomolgus (HEK293, His)

GM-CSF R α protein is an important type I cytokine receptor in the type 5 subfamily and plays an important role in mediating cellular responses to various cytokines. It shares conserved features with related receptors that transduce signals from specific type I cytokines, emphasizing its unique contribution to hematopoiesis and immune regulation in the broader context of cell signaling. GM-CSF R alpha Protein, Cynomolgus (298.a.a, HEK293, His) is the recombinant cynomolgus-derived GM-CSF R alpha protein, expressed by HEK293 , with C-His labeled tag.

The GM-CSF R alpha Protein is a critical member of the type I cytokine receptor family, specifically categorized within the Type 5 subfamily, highlighting its essential role in mediating cellular responses to various cytokines. As part of this receptor family, GM-CSF R alpha likely shares conserved structural and functional features with related receptors, emphasizing its involvement in transducing signals from specific type I cytokines. The classification within the type I cytokine receptor family underscores its specific designation within the broader context of cell signaling, providing insights into its unique contributions to hematopoiesis and immune regulation. The study of GM-CSF R alpha contributes to our understanding of its role in physiological processes, offering potential applications in therapeutic interventions for conditions related to hematopoietic disorders and immune dysregulation. Further exploration of GM-CSF R alpha's role holds promise for enhancing our knowledge of its contributions to both normal cellular function and pathological conditions.

Immobilized Cynomolgus GM-CSF R alpha, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-GM-CSF R alpha Antibody, hFc Tag with the EC₅₀ of 6.6 ng/ml determined by ELISA.

Cynomolgus

HEK293

C-His

A0A2K5UC70 (L20-S317)

/

60-70 kDa

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized powder.

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Normally 8% trehalose is added as protectant before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.