GPD1L Protein, Human (GST)

GPD1L protein regulates cardiac sodium current, with decreased enzymatic activity leading to elevated glycerol 3-phosphate levels.This activates the GPD1L-dependent SCN5A phosphorylation pathway, potentially resulting in reduced sodium current.Altered NAD(H) balance induced by GPD1L may also contribute to the decrease in cardiac sodium current.GPD1L Protein, Human (GST) is the recombinant human-derived GPD1L protein, expressed by E.coli , with N-GST labeled tag.

GPD1L protein is involved in the regulation of cardiac sodium current. A decrease in its enzymatic activity results in elevated glycerol 3-phosphate levels, activating the DPD1L-dependent SCN5A phosphorylation pathway, potentially leading to a reduction in sodium current. Additionally, changes in NAD(H) balance induced by GPD1L may contribute to the decrease in cardiac sodium current.

Human

E. coli

N-GST

Q8N335 (M1-T351)

23171  [NCBI]

MAAAPLKVCIVGSGNWGSAVAKIIGNNVKKLQKFASTVKMWVFEETVNGRKLTDIINNDHENVKYLPGHKLPENVVAMSNLSEAVQDADLLVFVIPHQFIHRICDEITGRVPKKALGITLIKGIDEGPEGLKLISDIIREKMGIDISVLMGANIANEVAAEKFCETTIGSKVMENGLLFKELLQTPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLRCGDNTKAAVIRLGLMEMIAFARIFCKGQVSTATFLESCGVADLITTCYGGRNRRVAEAFARTGKTIEELEKEMLNGQKLQGPQTSAEVYRILKQKGLLDKFPLFTAVYQICYESRPVQEMLSCLQSHPEHT

65.4 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.