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  3. HLA-A*0101 MAGE-A3 Complex Protein, Human (Biotinylated, EVDPIGHLY, HEK293, His-Avi)

HLA-A*0101 MAGE-A3 Complex Protein, Human (Biotinylated, EVDPIGHLY, HEK293, His-Avi)

Cat. No.: HY-P700935
Handling Instructions

HLA-A*0201 MAGE-A3 Complex Protein, a vital member of the major histocompatibility complex (MHC) class I family, facilitates immune recognition and response to hepatitis B virus (HBV). By presenting HBV-derived peptides to cytotoxic T cells, it contributes to antiviral defense mechanisms within the MHC class I pathway, emphasizing its pivotal role in adaptive immunity and immune system surveillance against infected or aberrant cells. HLA-A*0101 MAGE-A3 Complex Protein, Human (Biotinylated, EVDPIGHLY, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A*0101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and EVDPIGHLY peptide. HLA-A*0101 MAGE-A3 Complex Protein, Human (Biotinylated, EVDPIGHLY, HEK293, His-Avi), has molecular weight of 53-63 kDa.

For research use only. We do not sell to patients.

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Description

HLA-A*0201 MAGE-A3 Complex Protein, a vital member of the major histocompatibility complex (MHC) class I family, facilitates immune recognition and response to hepatitis B virus (HBV). By presenting HBV-derived peptides to cytotoxic T cells, it contributes to antiviral defense mechanisms within the MHC class I pathway, emphasizing its pivotal role in adaptive immunity and immune system surveillance against infected or aberrant cells. HLA-A*0101 MAGE-A3 Complex Protein, Human (Biotinylated, EVDPIGHLY, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A*0101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and EVDPIGHLY peptide. HLA-A*0101 MAGE-A3 Complex Protein, Human (Biotinylated, EVDPIGHLY, HEK293, His-Avi), has molecular weight of 53-63 kDa.

Background

The HLA-A*0201 HBV Complex Tetramer Protein is a member of the major histocompatibility complex (MHC) class I family, integral to the immune system's ability to recognize and respond to foreign antigens. As part of this family, the protein is involved in presenting viral peptides derived from hepatitis B virus (HBV) to cytotoxic T cells, contributing to the immune response against HBV infection. The MHC class I pathway, in which this protein participates, plays a crucial role in the surveillance and elimination of infected or aberrant cells by the immune system. The specific interaction of HLA-A*0201 with HBV-derived peptides underscores its significance in adaptive immunity, highlighting its role in antiviral defense mechanisms.

Species

Human

Source

HEK293

Tag

C-Avi;C-His

Accession

Q5SUL5 (G25-T305)&P61769 (I21-M119)&EVDPIGHLY

Gene ID

3105&567

Synonyms
MAGE family member A3; HIP8; HYPD; CT1.3; MAGE3; MAGEA6
Molecular Weight

53-63 kDa

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

HLA-A*0101 MAGE-A3 Complex Protein, Human (Biotinylated, EVDPIGHLY, HEK293, His-Avi) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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HLA-A*0101 MAGE-A3 Complex Protein, Human (Biotinylated, EVDPIGHLY, HEK293, His-Avi)
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