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LRPAP1 Protein, Mouse (HEK293, His, Solution)

Cat. No.: HY-P76479
SDS COA Handling Instructions

Low density lipoprotein receptor-related protein associated protein 1 interacts with the low density lipoprotein (LDL) receptor-related protein and facilitates its proper folding and localization by preventing the binding of ligands.LRPAP1 Protein, Mouse (HEK293, His, Solution) is the recombinant mouse-derived LRPAP1 protein, expressed by HEK293 , with C-His labeled tag.

For research use only. We do not sell to patients.

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Size Price Stock Quantity
5 μg $53 In-stock
10 μg $90 In-stock
50 μg $250 In-stock
100 μg   Get quote  

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Top Publications Citing Use of Products
  • Biological Activity

  • Technical Parameters

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  • Documentation

Description

Low density lipoprotein receptor-related protein associated protein 1 interacts with the low density lipoprotein (LDL) receptor-related protein and facilitates its proper folding and localization by preventing the binding of ligands.LRPAP1 Protein, Mouse (HEK293, His, Solution) is the recombinant mouse-derived LRPAP1 protein, expressed by HEK293 , with C-His labeled tag.

Background

Low density lipoprotein receptor-related protein associated protein 1 ( LRPAP1) interacts with the low density lipoprotein (LDL) receptor-related protein and facilitates its proper folding and localization by preventing the binding of ligands. LRPAP1 is a widely expressed gene that encodes low density lipoprotein receptor-related protein-associated protein 1, a 357 amino acid protein that is thought to act as a chaperone that binds and protects the lipoprotein receptor-related proteins LRP1 and LRP2[1][2][3][4].

Biological Activity

Measured by its binding ability in a functional ELISA . Immobilized mouse LRPAP1 at 0.5 μg/mL can bind human VLDLR with a linear range of 1.28-32 ng/mL.

Species

Mouse

Source

HEK293

Tag

C-His

Accession

Q52KI7 (Q29-L360)

Gene ID
Molecular Construction
N-term
LRPAP1 (Q29-L360)
Accession # Q52KI7
His
C-term
Synonyms
Alpha-2-macroglobulin receptor-associated protein; Alpha-2-MRAP; RAP; A2MRAP
Molecular Weight

Approximately 46 kDa.

Purity

Greater than 95% as determined by reducing SDS-PAGE

Appearance

Solution.

Formulation

Supplied as a 0.22 μm filtered solution of PBS, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

N/A.

Storage & Stability

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping

Shipping with dry ice.

Documentation

LRPAP1 Protein, Mouse (HEK293, His, Solution) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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LRPAP1 Protein, Mouse (HEK293, His, Solution)
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HY-P76479
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