1. Recombinant Proteins
  2. Cytokines and Growth Factors
  3. Neurotrophic Factors
  4. Neurotrophins/NGF
  5. Neurotrophin-3
  6. Neurotrophin-3 Protein, Human (HEK293)

Neurotrophin-3 Protein, Human (HEK293)

Cat. No.: HY-P702535
Handling Instructions

Neurotrophin-3 (NT-3) is crucial for promoting the survival of sensory neurons, specifically those linked to visceral and proprioceptive functions. Its role highlights NT-3's significance in maintaining and supporting the functionality of these specialized sensory cells, emphasizing its potential as a key regulator in the complex network governing essential physiological sensory processes. Neurotrophin-3 Protein, Human (HEK293) is the recombinant human-derived Neurotrophin-3 protein, expressed by HEK293 , with tag free. The total length of Neurotrophin-3 Protein, Human (HEK293) is 119 a.a., with molecular weight of 14 kDa.

For research use only. We do not sell to patients.

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Description

Neurotrophin-3 (NT-3) is crucial for promoting the survival of sensory neurons, specifically those linked to visceral and proprioceptive functions. Its role highlights NT-3's significance in maintaining and supporting the functionality of these specialized sensory cells, emphasizing its potential as a key regulator in the complex network governing essential physiological sensory processes. Neurotrophin-3 Protein, Human (HEK293) is the recombinant human-derived Neurotrophin-3 protein, expressed by HEK293 , with tag free. The total length of Neurotrophin-3 Protein, Human (HEK293) is 119 a.a., with molecular weight of 14 kDa.

Background

Neurotrophin-3 (NT-3) emerges as a crucial factor in fostering the survival of sensory neurons, particularly those associated with visceral and proprioceptive functions. Its role in supporting the viability of these specialized sensory cells underscores the significance of NT-3 in orchestrating the intricate mechanisms that contribute to the maintenance and functionality of visceral and proprioceptive neuronal populations. The specific actions of NT-3 in promoting neuronal survival shed light on its potential as a key regulator in the complex network governing sensory processes essential for proper physiological functioning.

Species

Human

Source

HEK293

Tag

Tag Free

Accession

P20783 (Y139-T257)

Gene ID

4908

Molecular Construction
N-term
Neurotrophin-3 (Y139-T257)
Accession # P20783
C-term
Synonyms
HDNF; MGC129711; Nerve growth factor 2; Neurotrophic factor; neurotrophin 3; neurotrophin-3; NGF2; NGF-2; NT3; NT-3; NTF3
AA Sequence

YAEHKSHRGEYSVCDSESLWVTDKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTSQTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGRT

Molecular Weight

Approximately 14 kDa

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Endotoxin Level

<0.1 EU/μg, determined by LAL method.

Documentation

Neurotrophin-3 Protein, Human (HEK293) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
Neurotrophin-3 Protein, Human (HEK293)
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HY-P702535
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