NKG2D/CD314 Protein, Mouse (sf9, Fc)

NKG2D is an activating cell surface receptor that associates selectively with DAP10, an YxxM-bearing adaptor protein.NKG2D/CD314 Protein, Mouse (sf9, Fc) is the recombinant mouse-derived NKG2D/CD314 protein, expressed by Sf9 insect cells , with N-hFc labeled tag.

NKG2D is an activating cell surface receptor that associates selectively with DAP10, an YxxM-bearing adaptor protein. NKG2D enables several functions, including MHC class I protein binding activity, MHC class Ib receptor activity and identical protein binding activity. NKG2D is involved in positive regulation of natural killer cell mediated cytotoxicity. NKG2D acts upstream of or within several processes, including positive regulation of interferon-gamma production, positive regulation of nitric oxide biosynthetic process and response to bacterium. NKG2D is located in external side of plasma membrane^[1][2][3].

Mouse

Sf9 insect cells

N-hFc

Q4FJM0 (F77-V219)

27007  [NCBI]

Approximately 44.9 kDa.

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.