2. Recombinant Proteins
  3. Cytokines and Growth Factors
  4. PDGFs & PDGFRs
  5. PDGF
  6. PDGF-A
  7. PDGFAA Protein, Canine (HEK293, Fc)

PDGFAA Protein, Canine (HEK293, Fc)

Cat. No.: HY-P75964
Handling Instructions

PDGFAA Protein is platelet-derived growth factor subunit A precursor. PDGFAA Protein, Canine (HEK293, Fc) is the recombinant canine-derived PDGFAA protein, expressed by HEK293 , with N-hFc labeled tag. The total length of PDGFAA Protein, Canine (HEK293, Fc) is 110 a.a., with molecular weight of ~41 kDa.

For research use only. We do not sell to patients.

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Description

PDGFAA Protein is platelet-derived growth factor subunit A precursor. PDGFAA Protein, Canine (HEK293, Fc) is the recombinant canine-derived PDGFAA protein, expressed by HEK293 , with N-hFc labeled tag. The total length of PDGFAA Protein, Canine (HEK293, Fc) is 110 a.a., with molecular weight of ~41 kDa.
Background

PDGFAA Protein is platelet-derived growth factor subunit A precursor. PDGFAA enables growth factor activity and platelet-derived growth factor receptor binding. PDGFAA is involved in platelet-derived growth factor receptor signaling pathway, positive regulation of MAP kinase activity and positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction[1][2][3].
Species

Canine
Source

HEK293
Tag

N-hFc
Accession

NP_001177101 (S87-R196)
Gene ID
Molecular Construction
N-term
hFc
PDGFAA (S87-R196)
Accession # NP_001177101
C-term
Synonyms
Platelet-derived growth factor subunit A; PDGF-1; PDGF-A; Rpa1
Molecular Weight

Approximately 41 kDa
Purity

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

PDGFAA Protein, Canine (HEK293, Fc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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