PRKD3/nPKC nu Protein, Human (sf9, GST)

PRKD3/nPKC nu protein acts as a mediator in the conversion of transient diacylglycerol (DAG) signals into sustained physiological effects, functioning downstream of PKC.Additionally, it plays a crucial role in conferring resistance to oxidative stress, demonstrating its involvement in cellular responses to environmental challenges.PRKD3/nPKC nu Protein, Human (sf9, GST) is the recombinant human-derived PRKD3/nPKC nu protein, expressed by Sf9 insect cells , with GST labeled tag.

Protein kinase D3 (PRKD3), also known as novel protein kinase C nu (nPKC nu), serves a crucial role in cellular signaling by converting transient diacylglycerol (DAG) signals into sustained physiological effects, acting downstream of protein kinase C (PKC). This kinase's ability to modulate signaling cascades suggests its involvement in diverse cellular processes that rely on prolonged responses to diacylglycerol. Furthermore, PRKD3/nPKC nu has been implicated in conferring resistance to oxidative stress, indicating its potential role in cellular defense mechanisms against reactive oxygen species and related stressors (By similarity). The multifaceted functions of PRKD3/nPKC nu underscore its importance in signal transduction, suggesting its contribution to cellular adaptation and survival in response to various environmental challenges.

Human

Sf9 insect cells

GST

O94806 (S2-P890)

23683  [NCBI]

Approximately 126.7 kDa

Greater than 85% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.