Prolactin R Protein, Cynomolgus (HEK293, His)

The prolactin R protein is a receptor for prolactin that promotes multiple molecular interactions, such as association with SMARCA1, suggesting a possible involvement in chromatin remodeling. Its prolactin-dependent interaction with NEK3 and VAV2 suggests interactions that regulate responses to stimuli. Prolactin R Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Prolactin R protein, expressed by HEK293 , with C-His labeled tag. The total length of Prolactin R Protein, Cynomolgus (HEK293, His) is 212 a.a., with molecular weight of 35-50 kDa.

Prolactin R Protein functions as a receptor specifically designed for the anterior pituitary hormone prolactin. Facilitating cellular responses to prolactin, this receptor engages in diverse molecular interactions, including its association with SMARCA1, suggesting potential involvement in chromatin remodeling processes. Additionally, Prolactin R Protein interacts with NEK3 and VAV2 in a prolactin-dependent manner, indicating a regulated interplay in response to prolactin stimulation. These interactions underscore the receptor's pivotal role in transducing prolactin-mediated signals, influencing cellular processes, and contributing to the regulation of diverse physiological functions.

Immobilized Cynomolgus PRLR, His Tag at 5 μg/mL (100 μl/well) on the plate. Dose response curve for Anti-PRLR Antibody, hFc Tag with the EC₅₀ of ≤35 ng/mL determined by ELISA.

Cynomolgus

HEK293

C-His

A0A2K5WXK1 (Q25-T236)

102139140

35-50 kDa, due to glycosylation

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized powder

Lyophilized from a 0.22 μm filtered solution of 50mM Tris, 150mM NaCl, pH 7.5. Normally 8% trehalose is added as protectant before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.