Protein L Protein, Finegoldia magna (Biotinylated, HEK293, His-Avi)

L protein is derived from *Peptostreptococcus* and selectively binds to the immunoglobulin kappa light chain without interacting with the Fc region. This property can be used in antibody purification, diagnostics, and research to selectively isolate antibodies based on their light chain composition. Protein L Protein, Finegoldia magna (Biotinylated, HEK293, His-Avi) is the recombinant protein L protein, expressed by HEK293 , with N-His, N-Avi labeled tag. The total length of Protein L Protein, Finegoldia magna (Biotinylated, HEK293, His-Avi) is 365 a.a., with molecular weight of ~50 kDa.

Protein L is a bacterial immunoglobulin-binding protein produced by *Peptostreptococcus magnus*. It specifically binds to the kappa light chains of immunoglobulins (Ig) and does not interact with the Fc region. Protein L has applications in antibody purification, diagnostics, and research, where it enables the selective isolation of antibodies based on their light chain composition. This unique property makes Protein L a valuable tool in various biotechnological and biomedical applications involving antibody manipulation and analysis.

Measured by its binding ability in a functional ELISA. Immoilized Ipilimumab antibody at 2 μg/mL can bind Biotinylated Protein L. The EC ₅₀ is 1.123-1.761 ng/mL.

Others

HEK293

N-His;N-Avi

D6S9W1 (K106-G470)

/

Approximately 50 kDa

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized powder

Lyophilized a 0.22 μm filtered solution of PBS, 6% Trehalose, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.