RAB6A Protein, Human (His)

RAB6A protein forms a complex with BICD1 and directly interacts with DYNLRB1 in the GDP-bound state, suggesting a regulatory role in coordinating cellular functions. In the GTP-bound state, RAB6A interacts with VPS13B, suggesting involvement in VPS13B-related pathways. RAB6A Protein, Human (His) is the recombinant human-derived RAB6A protein, expressed by E. coli , with N-His labeled tag. The total length of RAB6A Protein, Human (His) is 208 a.a., with molecular weight of ~26 kDa.

The RAB6A protein engages in specific interactions within cellular processes, forming a complex with BICD1 as evidenced by studies. Additionally, RAB6A demonstrates direct interaction with DYNLRB1 when in its GDP-bound state. This interaction suggests a regulatory role for RAB6A in coordinating cellular functions associated with DYNLRB1. Moreover, in its GTP-bound state, RAB6A interacts with VPS13B, indicating its involvement in molecular pathways associated with VPS13B. These interactions highlight the versatile nature of RAB6A in modulating various cellular processes and emphasize the need for further exploration to unravel the specific roles and regulatory mechanisms underlying these associations.

Human

E. coli

N-His

P20340-2 (M1-C208)

5870  [NCBI]

MSTGGDFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQERFRSLIPSYIRDSAAAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIIMLVGNKTDLADKRQVSIEEGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGMESTQDRSREDMIDIKLEKPQEQPVSEGGCSC

Approximately 26 kDa

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized powder

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.