SCARB2/LIMP-2 Protein, Human (HEK293, His)

SCARB2/LIMP-2 Protein functions as a lysosomal receptor, specifically guiding glucosylceramidase (GBA1) to lysosomes. Additionally, it serves as a receptor for enterovirus 71, emphasizing its role in mediating cellular interactions during viral invasion and cellular entry processes. SCARB2/LIMP-2 Protein, Human (HEK293, His) is the recombinant human-derived SCARB2/LIMP-2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of SCARB2/LIMP-2 Protein, Human (HEK293, His) is 406 a.a., with molecular weight of 62-100 kDa.

SCARB2/LIMP-2 Protein serves as a lysosomal receptor specifically responsible for targeting glucosylceramidase (GBA1) to the lysosomes. Additionally, in the context of microbial infection, it acts as a receptor for enterovirus 71, highlighting its role in facilitating cellular interactions during viral invasion and cellular entry processes.

Human

HEK293

C-6*His

Q14108 (R27-T432)

950  [NCBI]

RVFQKAVDQSIEKKIVLRNGTEAFDSWEKPPLPVYTQFYFFNVTNPEEILRGETPRVEEVGPYTYRELRNKANIQFGDNGTTISAVSNKAYVFERDQSVGDPKIDLIRTLNIPVLTVIEWSQVHFLREIIEAMLKAYQQKLFVTHTVDELLWGYKDEILSLIHVFRPDISPYFGLFYEKNGTNDGDYVFLTGEDSYLNFTKIVEWNGKTSLDWWITDKCNMINGTDGDSFHPLITKDEVLYVFPSDFCRSVYITFSDYESVQGLPAFRYKVPAEILANTSDNAGFCIPEGNCLGSGVLNVSICKNGAPIIMSFPHFYQADERFVSAIEGMHPNQEDHETFVDINPLTGIILKAAKRFQINIYVKKLDDFVETGDIRTMVFPVMYLNESVHIDKETASRLKSMINTT

62-100 kDa

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized powder.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US;may vary elsewhere.