1. Recombinant Proteins
  2. Enzymes & Regulators
  3. Transferases (EC 2)
  4. SLK Protein, Human (Sf9, GST)

SLK Protein, Human (Sf9, GST)

Cat. No.: HY-P701633
Handling Instructions

The SLK protein is a bifunctional mediator that affects apoptosis and actin stress fiber lysis, suggesting a role in programmed cell death and regulation of cytoskeletal dynamics. The specific molecular mechanisms coordinating these processes need to be further elucidated to facilitate research on the functional significance of SLK. SLK Protein, Human (Sf9, GST) is the recombinant human-derived SLK protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of SLK Protein, Human (Sf9, GST) is 1152 a.a., .

For research use only. We do not sell to patients.

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Description

The SLK protein is a bifunctional mediator that affects apoptosis and actin stress fiber lysis, suggesting a role in programmed cell death and regulation of cytoskeletal dynamics. The specific molecular mechanisms coordinating these processes need to be further elucidated to facilitate research on the functional significance of SLK. SLK Protein, Human (Sf9, GST) is the recombinant human-derived SLK protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of SLK Protein, Human (Sf9, GST) is 1152 a.a., .

Background

SLK Protein emerges as a mediator with dual functionality, implicated in both apoptosis and the dissolution of actin stress fibers. Its role in apoptosis suggests a potential influence on programmed cell death pathways, while its involvement in actin stress fiber dissolution underscores its significance in regulating the cytoskeletal dynamics of cells. The specific molecular mechanisms through which SLK orchestrates these processes remain to be fully elucidated, prompting further investigation into its functional significance in cellular events. The dual role proposed for SLK in apoptosis and actin stress fiber dissolution highlights its versatility in influencing critical cellular processes, warranting in-depth studies to unravel the precise molecular pathways through which SLK exerts its effects and its broader implications in cellular regulation.

Species

Human

Source

Sf9 insect cells

Tag

N-GST

Accession

Q9H2G2 (M1-T1152)

Gene ID

9748

Molecular Construction
N-term
GST
SLK (M1-T1152)
Accession # Q9H2G2
C-term
Synonyms
SLK; STE20-like serine/threonine-protein kinase; STE20-like kinase; hSLK; CTCL tumor antigen se20-9; STE20-related serine/threonine-protein kinase; STE20-related kinase; Serine/threonine-protein kinase 2
Purity

Greater than 90% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

SLK Protein, Human (Sf9, GST) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
SLK Protein, Human (Sf9, GST)
Cat. No.:
HY-P701633
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