SNTG1 Protein, Human (Myc, His)

SNTG1 acts as an adapter protein that binds and potentially organizes various proteins, serving as a link between the receptor and the actin cytoskeleton or dystrophin glycoprotein complex. It may modulate the subcellular distribution of diacylglycerol kinase-zeta and contribute to the rapid inactivation of diacylglycerol upon receptor activation. SNTG1 Protein, Human (Myc, His) is the recombinant human-derived SNTG1 protein, expressed by E. coli , with N-His, C-Myc labeled tag.

SNTG1 functions as an adapter protein with the capacity to bind and likely organize the subcellular localization of diverse proteins, potentially serving as a link between various receptors and the actin cytoskeleton as well as the dystrophin glycoprotein complex. It may play a role in regulating the subcellular distribution of diacylglycerol kinase-zeta to facilitate the prompt inactivation of diacylglycerol following receptor activation. Notably, isoform 1 of SNTG1, in contrast to isoform 2, engages in interactions with the dystrophin protein DMD and its related counterparts DTNA and DTNB. Additionally, SNTG1 forms an interaction with DGKZ, suggesting its involvement in modulating the cellular dynamics of key signaling molecules and structural components.

Human

E. coli

N-His;C-Myc

Q9NSN8-1 (M1-T517)

54212  [NCBI]

MDFRTACEETKTGICLLQDGNQEPFKVRLHLAKDILMIQEQDVICVSGEPFYSGERTVTIRRQTVGGFGLSIKGGAEHNIPVVVSKISKEQRAELSGLLFIGDAILQINGINVRKCRHEEVVQVLRNAGEEVTLTVSFLKRAPAFLKLPLNEDCACAPSDQSSGTSSPLCDSGLHLNYHPNNTDTLSCSSWPTSPGLRWEKRWCDLRLIPLLHSRFSQYVPGTDLSRQNAFQVIAVDGVCTGIIQCLSAEDCVDWLQAIATNISNLTKHNIKKINRNFPVNQQIVYMGWCEAREQDPLQDRVYSPTFLALRGSCLYKFLAPPVTTWDWTRAEKTFSVYEIMCKILKDSDLLDRRKQCFTVQSESGEDLYFSVELESDLAQWERAFQTATFLEVERIQCKTYACVLESHLMGLTIDFSTGFICFDAATKAVLWRYKFSQLKGSSDDGKSKIKFLFQNPDTKQIEAKELEFSNLFAVLHCIHSFFAAKVACLDPLFLGNQATASTAASSATTSKAKYTT

Approximately 63.0 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.