1. Recombinant Proteins
  2. Enzymes & Regulators
  3. Serine/Threonine Kinase Proteins
  4. Serine/Threonine Kinase 40
  5. STK40 Protein, Human (sf9, His-GST)

STK40 Protein, Human (sf9, His-GST)

Cat. No.: HY-P76098
Handling Instructions

The STK40 protein functions as a potential negative regulator, inhibiting NF-kappa-B and p53-mediated gene transcription. Its regulatory role implies fine-tuning of signaling pathways, indicating regulation of gene expression. STK40 Protein, Human (sf9, His-GST) is the recombinant human-derived STK40 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.

For research use only. We do not sell to patients.

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Description

The STK40 protein functions as a potential negative regulator, inhibiting NF-kappa-B and p53-mediated gene transcription. Its regulatory role implies fine-tuning of signaling pathways, indicating regulation of gene expression. STK40 Protein, Human (sf9, His-GST) is the recombinant human-derived STK40 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.

Background

STK40 Protein emerges as a potential negative regulator, exerting influence over NF-kappa-B and p53-mediated gene transcription. Its regulatory role implies an inhibitory function, suggesting involvement in fine-tuning the intricate signaling pathways associated with NF-kappa-B and p53. By acting as a negative regulator, STK40 may modulate the expression of genes under the control of these transcription factors, influencing cellular responses to various stimuli. Elucidating the specific mechanisms through which STK40 exerts its regulatory effects on NF-kappa-B and p53-mediated transcription could provide valuable insights into its role in cellular homeostasis and response to stressors. Further exploration of STK40's interactions and downstream effects may contribute to a comprehensive understanding of its function in the intricate network of transcriptional regulation.

Species

Human

Source

Sf9 insect cells

Tag

N-His;N-GST

Accession

Q8N2I9-1 (M1-K435)

Gene ID
Molecular Construction
N-term
His-GST
STK40 (M1-K435)
Accession # Q8N2I9-1
C-term
Synonyms
Serine/threonine-protein kinase 40; Sugen kinase 495; SgK495; STK40; SGK495; SHIK
Molecular Weight

Approximately 85 kDa

Purity

Greater than 95% as determined by reducing SDS-PAGE

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

STK40 Protein, Human (sf9, His-GST) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
STK40 Protein, Human (sf9, His-GST)
Cat. No.:
HY-P76098
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