Uteroglobin/SCGB1A1 Protein, Human

Uteroglobin/SCGB1A1 Protein displays diverse binding, including phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB), and weakly binds progesterone. It acts as a robust inhibitor of phospholipase A2, structurally forming a disulfide-linked antiparallel homodimer. Controversy surrounds its interaction with LMBR1L, necessitating further investigation. Uteroglobin/SCGB1A1 Protein, Human is the recombinant human-derived Uteroglobin/SCGB1A1 protein, expressed by E. coli , with tag free. The total length of Uteroglobin/SCGB1A1 Protein, Human is 70 a.a., with molecular weight of ~7.9 kDa.

The Uteroglobin/SCGB1A1 protein exhibits versatile binding capabilities, including the ability to bind phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB), and weakly binds progesterone. Additionally, it functions as a potent inhibitor of phospholipase A2. Structurally, this protein forms an antiparallel homodimer that is disulfide-linked. While there is some controversy surrounding its interaction with LMBR1L, further investigation is required to clarify this aspect.

Measured by the ability of the immobilized protein to support the adhesion of the A549 human lung carcinoma cells. The ED₅₀ for this effect is typically 0.2278 μg/mL, corresponding to a specific activity is 4.390×10³ units/mg.

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  Measured by the ability of the immobilized protein to support the adhesion of the A549 human lung carcinoma cells. The ED₅₀ for this effect is typically 0.2278 μg/mL, corresponding to a specific activity is 4.390×10³ units/mg.

Human

E. coli

Tag Free

P11684 (E22-N91)

7356  [NCBI]

EICPSFQRVIETLLMDTPSSYEAAMELFSPDQDMREAGAQLKKLVDTLPQKPRESIIKLMEKIAQSSLCN

Approximately 7.9 kDa

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  Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized powder.

Lyophilized from a 0.2 μm concentrated solution in PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in sterile distilled water. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US;may vary elsewhere.