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  5. Rhizopodin

Rhizopodin is a new cytostatic compound isolated from the culture fluid of the slime mold Myxococcus stipitatus. Rhizopodin inhibits the growth of various animal cell cultures without killing the cells, with an ID50 value of 12 to 30 ng/ml, depending on the cell line. In particular, fibroblast-like cells show typical morphological changes, with cells becoming larger and forming long branched reticular extensions within hours, and these morphological changes are irreversible. Rhizopodin inhibits bleb formation in K-562 cells, possibly through interaction with protein phosphorylation.

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Rhizopodin Chemical Structure

Rhizopodin Chemical Structure

CAS No. : 150346-23-9

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Rhizopodin Related Antibodies

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Description

Rhizopodin is a new cytostatic compound isolated from the culture fluid of the slime mold Myxococcus stipitatus. Rhizopodin inhibits the growth of various animal cell cultures without killing the cells, with an ID50 value of 12 to 30 ng/ml, depending on the cell line. In particular, fibroblast-like cells show typical morphological changes, with cells becoming larger and forming long branched reticular extensions within hours, and these morphological changes are irreversible. Rhizopodin inhibits bleb formation in K-562 cells, possibly through interaction with protein phosphorylation.

Molecular Weight

1469.83

Formula

C78H124N4O22
CAS No.
SMILES

CO[C@]1([H])C2=COC(C[C@@H](C(C)([C@@H](OC(C[C@H](C[C@H](/C=C/C=C/C[C@@](OC)([H])C3=COC(C[C@H](O)C(C)(C)[C@H](C[C@H](OC)[C@@H](C)CCC([C@H](C)[C@H](OC)C/C=C/N(C)C=O)=O)OC(C[C@@H](O)C[C@@H](OC)/C=C/C=C/C1)=O)=N3)OC)O)=O)C[C@H](OC)[C@@H](C)CCC([C@H](C)[C@H](OC)C/C=C/N(C)C=O)=O)C)O)=N2
Structure Classification
Initial Source

Myxococcus stipitatus
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Rhizopodin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Rhizopodin150346-23-9OthersInhibitorinhibitorinhibit

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