1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Rociverine

Rociverine is an anticholinergic compound with smooth muscle relaxant activity. Rociverine showed different binding modes in five cloned muscarinic receptors. The cis stereoisomer of Rociverine showed a higher affinity change compared to the trans stereoisomer. The (1R,2R) configuration of Rociverine showed significantly higher affinity, even up to 240 times. The (1S,2S) configuration of Rociverine is very important for binding selectivity.

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Rociverine Chemical Structure

Rociverine Chemical Structure

CAS No. : 53716-44-2

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Description

Rociverine is an anticholinergic compound with smooth muscle relaxant activity. Rociverine showed different binding modes in five cloned muscarinic receptors. The cis stereoisomer of Rociverine showed a higher affinity change compared to the trans stereoisomer. The (1R,2R) configuration of Rociverine showed significantly higher affinity, even up to 240 times. The (1S,2S) configuration of Rociverine is very important for binding selectivity[1].

Molecular Weight

339.51

Formula

C20H37NO3

CAS No.
SMILES

O[C@@]1(C2CCCCC2)[C@H](CCCC1)C(OC(C)CN(CC)CC)=O

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Rociverine
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HY-122294
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