2. Metabolic Enzyme/Protease Vitamin D Related/Nuclear Receptor Cell Cycle/DNA Damage Others
  3. ROR Dihydroorotate Dehydrogenase DNA/RNA Synthesis Isotope-Labeled Compounds
  4. RORγ/DHODH-IN-1

RORγ/DHODH-IN-1 (compound 1404), a deuterium labeled compound, is a dual RORγ and DHODH inhibitor with IC50 values of 9.7 nM and 100 nM, repaectively. RORγ/DHODH-IN-1 blocks the replication of SARS-CoV-2, HCMV, and non-enveloped DNA virus (HAdV5).

For research use only. We do not sell to patients.

RORγ/DHODH-IN-1 Chemical Structure

RORγ/DHODH-IN-1 Chemical Structure

CAS No. : 3000567-76-7

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RORγ/DHODH-IN-1 Related Antibodies

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Description

RORγ/DHODH-IN-1 (compound 1404), a deuterium labeled compound, is a dual RORγ and DHODH inhibitor with IC50 values of 9.7 nM and 100 nM, repaectively. RORγ/DHODH-IN-1 blocks the replication of SARS-CoV-2, HCMV, and non-enveloped DNA virus (HAdV5)[1].

Molecular Weight

514.30

Formula

C23H13D2Cl2F4N3O2
CAS No.
SMILES

ClC(C=CC=C1F)=C1C2=NOC(C3=C(N(C4=CC(Cl)=CC=C4)N=C3)C(F)(F)F)=C2C([2H])([2H])OC5CC5
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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RORγ/DHODH-IN-1 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RORγ/DHODH-IN-13000567-76-7RORDihydroorotate DehydrogenaseDNA/RNA SynthesisIsotope-Labeled CompoundsRAR-related orphan receptorDHODHRORγDHODH inhibitorSARS-CoV-2HCMVHAdV5Inhibitorinhibitorinhibit

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