2. GPCR/G Protein Neuronal Signaling
  3. mGluR
  4. (RS)-4C3HPG

(RS)-4C3HPG  (Synonyms: 4-Carboxy-3-hydroxyphenylglycine)

Cat. No.: HY-100840A
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(RS)-4C3HPG (4-Carboxy-3-hydroxyphenylglycine) is an effective competitive antagonist at the metabotropic glutamate receptor 1 (mGluR1) in the central nervous system, and it is also an agonist at mGluR2/3. (RS)-4C3HPG exhibits neuroprotective effects in an acute global ischemia rat model.

For research use only. We do not sell to patients.

(RS)-4C3HPG Chemical Structure

(RS)-4C3HPG Chemical Structure

CAS No. : 134052-66-7

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Other Forms of (RS)-4C3HPG:

(RS)-4C3HPG Related Antibodies

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Description

(RS)-4C3HPG (4-Carboxy-3-hydroxyphenylglycine) is an effective competitive antagonist at the metabotropic glutamate receptor 1 (mGluR1) in the central nervous system, and it is also an agonist at mGluR2/3. (RS)-4C3HPG exhibits neuroprotective effects in an acute global ischemia rat model[1][2].

IC50 & Target

mGluR 1

 

mGluR2

 

mGluR3

 

Molecular Weight

211.17

Formula

C9H9NO5
CAS No.
SMILES

O=C(O)C(N)C1=CC=C(C(O)=O)C(O)=C1
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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(RS)-4C3HPG Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(RS)-4C3HPG134052-66-74-Carboxy-3-hydroxyphenylglycinemGluRMetabotropic glutamate receptorsNeuroprotectiveInhibitorinhibitorinhibit

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