2. MAPK/ERK Pathway
  3. Ribosomal S6 Kinase (RSK)
  4. RSK2-IN-2

RSK2-IN-2 (Compound 25) is a reversible covalent inhibitor of the RPS6KA3 (RSK2) kinase. RSK2-IN-2 is also described to inhibit MSK1, MSK2 and RSK3.

For research use only. We do not sell to patients.

RSK2-IN-2 Chemical Structure

RSK2-IN-2 Chemical Structure

CAS No. : 1637749-78-0

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RSK2-IN-2 Related Antibodies

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Description

RSK2-IN-2 (Compound 25) is a reversible covalent inhibitor of the RPS6KA3 (RSK2) kinase. RSK2-IN-2 is also described to inhibit MSK1, MSK2 and RSK3[1].

IC50 & Target

RSK2

 

RSK3

 

MSK1

 

MSK2

 

In Vitro

RSK2-IN-2 (Compound 25) shows strong activity with ERK2-MSK1 cascade pIC50 of 9.6[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

RSK2-IN-2 Related Antibodies
Molecular Weight

289.29

Formula

C16H11N5O
CAS No.
SMILES

O=C(N)/C(C#N)=C/C1=CC=CC(C2=C3C(NC=C3)=NC=N2)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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RSK2-IN-2 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RSK2-IN-21637749-78-0Ribosomal S6 Kinase (RSK)S6KRPS6KA3MSK2MSK1Inhibitorinhibitorinhibit

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RSK2-IN-2
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HY-150643
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