2. Vitamin D Related/Nuclear Receptor
  3. Androgen Receptor
  4. RU 58642

RU 58642 is an orally active non-steroidal antiandrogen, which displays a strong and selective affinity for androgen receptor.

For research use only. We do not sell to patients.

RU 58642 Chemical Structure

RU 58642 Chemical Structure

CAS No. : 143782-63-2

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RU 58642 Related Antibodies

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Description

RU 58642 is an orally active non-steroidal antiandrogen, which displays a strong and selective affinity for androgen receptor[1].

In Vivo

In vivo, the antiandrogenic activity of RU-58642 is evaluated in castrated rat supplemented with testosterone propionate and in intact animals on prostate, seminal vesicles weight and serum levels of testosterone by oral and subcutaneous route. In rats, RU 58642 induces a significant decrease in prostate weight at a dose as low as 0.3 mg/kg whatever the route of administration[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

336.27

Formula

C15H11F3N4O2
CAS No.
SMILES

N#CCN(C(C)(C1=O)C)C(N1C2=CC=C(C(C(F)(F)F)=C2)C#N)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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RU 58642 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RU 58642143782-63-2RU58642RU-58642Androgen Receptorantiandrogenorally activeInhibitorinhibitorinhibit

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