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  4. [Ru(dppn)2phen](PF6)2

[Ru(dppn)2phen](PF6)2 (compound 4) is a polypyridylruthenium compound used in photodynamic therapy (PDT). [Ru(dppn)2phen](PF6)2 is normally nontoxic under dark conditions and induces mitochondrial respiratory damage upon light exposure. [Ru(dppn)2phen](PF6)2 exhibits high levels of singlet oxygen quantum yield and phototoxicity against cancer cells.

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[Ru(dppn)2phen](PF6)2 Chemical Structure

[Ru(dppn)2phen](PF6)2 Chemical Structure

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[Ru(dppn)2phen](PF6)2 Related Antibodies

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Description

[Ru(dppn)2phen](PF6)2 (compound 4) is a polypyridylruthenium compound used in photodynamic therapy (PDT). [Ru(dppn)2phen](PF6)2 is normally nontoxic under dark conditions and induces mitochondrial respiratory damage upon light exposure. [Ru(dppn)2phen](PF6)2 exhibits high levels of singlet oxygen quantum yield and phototoxicity against cancer cells[1].

Molecular Weight

1235.92

Formula

C56H32F12N10P2Ru
SMILES

[F-][P+5]([F-])([F-])([F-])([F-])[F-].[F-][P+5]([F-])([F-])([F-])([F-])[F-].C12=CC3=NC4=C(N=C3C=C1C=CC=C2)C5=C6C7=C4C=CC=[N]7[Ru+2]89([N]6=CC=C5)([N]%10=CC=CC%11=C%10C%12=C(C=CC=[N]%129)C%13=C%11N=C%14C=C%15C=CC=CC%15=CC%14=N%13)[N]%16=C%17C(C=CC%18=C%17[N]8=CC=C%18)=CC=C%16
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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[Ru(dppn)2phen](PF6)2 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

[Ru(dppn)2phen](PF6)2Othersphotosensitizerphotodynamic therapyInhibitorinhibitorinhibit

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