2. Anti-infection
  3. SARS-CoV
  4. SARS-CoV-2 Mpro-IN-37

SARS-CoV-2 Mpro-IN-37 (compound 8r) is a SARS-CoV-2 main protease (Mpro) inhibitor, with an IC50 of 0.0199 μM. SARS-CoV-2 Mpro-IN-37 inhibits SARS-CoV-1 Mpro and MERS-CoV Mpro with IC50s of 0.00945 and 0.111 μM, respectively. SARS-CoV-2 Mpro-IN-37 displays high antiviral activity in the nanomolar range without showing cellular toxicity.

For research use only. We do not sell to patients.

SARS-CoV-2 Mpro-IN-37 Chemical Structure

SARS-CoV-2 Mpro-IN-37 Chemical Structure

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SARS-CoV-2 Mpro-IN-37 Related Antibodies

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Description

SARS-CoV-2 Mpro-IN-37 (compound 8r) is a SARS-CoV-2 main protease (Mpro) inhibitor, with an IC50 of 0.0199 μM. SARS-CoV-2 Mpro-IN-37 inhibits SARS-CoV-1 Mpro and MERS-CoV Mpro with IC50s of 0.00945 and 0.111 μM, respectively. SARS-CoV-2 Mpro-IN-37 displays high antiviral activity in the nanomolar range without showing cellular toxicity[1].

Molecular Weight

438.58

Formula

C25H30N2O3S
SMILES

CC(C)C[C@H](NC(CSC1=CC=CC=C1)=O)C(N[C@H](C(C=C)=O)CC2=CC=CC=C2)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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SARS-CoV-2 Mpro-IN-37 Related Classifications

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SARS-CoV-2 Mpro-IN-37SARS-CoVSARS coronavirusantiviralmetabolic stabilityCalu-3 cellsInhibitorinhibitorinhibit

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