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(S)-JNJ-75276617

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-148669B
    (S)-Bleximenib oxalate

    (S)-JNJ-75276617 oxalate; (S)-Menin-MLL inhibitor 24 oxalate

    		 Apoptosis Histone Methyltransferase FLT3 Cancer
    (S)-Bleximenib (oxalate) is a S-Enantiomer of Bleximenib oxalate (HY-148669A). Bleximenib (JNJ-75276617) oxalate is an orally active and selective menin-KMT2A inhibitor, with IC50 values of 0.1 nM, 0.045 nM, and ≤0.066 nM for humans, mice, and dogs, respectively. Bleximenib oxalate can inhibit the proliferation and induce apoptosis and differentiation of tumor cells. Bleximenib oxalate can be used in the research of tumors such as leukemia .
    (S)-Bleximenib oxalate

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