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BVDU

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-13578
    Brivudine
    1 Publications Verification

    Bromovinyldeoxyuridine; BVDU

    		 CMV Infection Cancer
    Brivudine is a thymidine analogue with antiviral activity, indicated for the early treatment of acute herpes zoster.
    Brivudine
  • HY-W747737A
    BVDU 5′-Triphosphate ammonium

    (E)-5-(2-Bromovinyl)-dUTP ammonium; BVDUTP ammonium

    		 HSV Infection
    BVDU 5′-Triphosphate ammonium is an antivirus agent with 5′-Triphosphate label, targeting viral DNA polymerase. BVDU 5′-Triphosphate ammonium shows excellent selectivity against varicella-zoster virus (VZV) and herpes simplex virus type 1 (HSV-1), due to a specific phosphorylation by the virus-encoded thymidine kinase.
    BVDU 5′-Triphosphate ammonium
  • HY-106168
    Thymectacin

    NB1011

    		 Others Cancer
    Thymectacin (NB1011) is an agent selectively targeting tumor cells that have a high expression of thymidylate synthase (TS). Thymectacin is an aryloxy phosphoramidate derivative of BVdU (brivudin) .
    Thymectacin
  • HY-W747737
    BVDU 5′-Triphosphate

    (E)-5-(2-Bromovinyl)-dUTP; BVDUTP

    		 DNA/RNA Synthesis HSV Infection
    BVDU 5′-Triphosphate is an antivirus agent with 5′-Triphosphate label, targeting viral DNA polymerase. BVDU 5′-Triphosphate shows excellent selectivity against varicella-zoster virus (VZV) and herpes simplex virus type 1 (HSV-1), due to a specific phosphorylation by the virus-encoded thymidine kinase.
    BVDU 5′-Triphosphate
  • HY-W747736
    BVdUMP

    BVDU 5'-monophosphate

    		 Others Others
    BVdUMP is an active compound.
    BVdUMP
  • HY-148653
    (+)-C-BVDU

    		Others Others
    (+)-C-BVDU is an active compound.
    (+)-C-BVDU
  • HY-W014109
    (E)-5-(2-Bromovinyl)pyrimidine-2,4(1H,3H)-dione

    (E)-5-(2-Bromovinyl)uracil; BVU

    		 Others Infection
    (E)-5-(2-Bromovinyl)uracil (BVU) is a pyrimidine base and an inactive metabolite of the antiviral agents sorivudine and (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) that may be regenerated to BVDU in vivo. BVU irreversibly inactivates dihydropyrimidine dehydrogenase (DPD) in an NADPH-dependent manner. It enhances the efficacy of the chemotherapeutic agent and DPD substrate 5-fluorouracil (HY-90006) in a P388 murine leukemia model when administered at a dose of 200 μmol/kg, increasing survival time.
    (E)-5-(2-Bromovinyl)pyrimidine-2,4(1H,3H)-dione

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